Was sind Prostaglandinanaloga?
Prostaglandinanaloga werden zur Senkung eines erhöhten Augeninnendrucks, z.B. im Rahmen eines Glaukoms, eingesetzt. Die Applikation erfolgt über Augentropfen.
Welche Augentropfen enthalten Prostaglandine?
Prostaglandine Bimatoprost, Latanoprost, Tafluprost und Travoprost (Augentropfen)
Was bewirken Prostaglandine im Körper?
Prostaglandine sind von der Arachidonsäure abgeleitete Lokalhormone aus der Klasse der Eikosanoide. Sie spielen eine Rolle bei der lokalen Schmerzvermittlung (Schmerzmediator) und als Mediatoren für die Wirkung von Hormonen, sowie bei integrativen Funktionen wie der Entstehung von Fieber bei Entzündungsprozessen.
What is a prostaglandin analogue?
Prostaglandin analogue. Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects and their abortive potential.
How do prostaglandin E1 analogues work?
Alprostadil is a synthetic prostaglandin E 1 analogue. It vasodilates by acting on smooth muscle cell surface receptors to increase intracellular cyclic adenosine monophosphate (cAMP), which in turn reduces the intracellular Ca 2+ concentration.
What can prostaglandin analogs do for hair growth?
Even though the exact mechanism is unknown, it has been established that prostaglandin F2 α analogs cause hair growth by stimulating and extending the anagen (growing) phase, increasing the proportion of anagen compared to catagen and telogen hair ( 2, 7 ). Hence, most hair strands remain long, coarse, and darker (terminal hair).
Can NSAIDs and prostaglandin analogues be combined?
Prostaglandins act directly on the prostanoid receptor, and NSAIDs exert their effect through inhibiting production/release of prostaglandins in the tissue, one would not expect an interaction between the two drugs. Thus, combining prostaglandin analogues and an oral NSAID has never been considered a problem.