Inhaltsverzeichnis
Was heisst Spondyloarthritis?
Die Spondyloarthritiden sind durch eine Entzündung der Wirbelsäule mit der Tendenz zur Verknöcherung charakterisiert. Neben der Wirbelsäule können auch insbesondere größere Gelenke der unteren Extremität betroffen sein.
Wie heißt der Labormarker bei Morbus Bechterew?
Die Häufigkeit des Morbus Bechterew ist gekoppelt an das Vorkommen des Genmarkers HLA-B27. Etwa 90\%-95\% aller gesicherten Morbus Bechterew-Fälle tragen diesen Genmarker – also tragen etwa 10\% den Marker nicht. Aber von allen Menschen, die den Genmarker HLA-B27 tragen, erkrankt nur ein kleiner Teil an Morbus Bechterew.
What is seronegative spondyloarthritis?
A type of autoimmune, inflammatory disease that affects the joints and the etheses resulting in pain, swelling and stiffness. Seronegative spondyloarthritis is an umbrella term for autoimmune, inflammatory diseases that involve both the joints and the entheses (the sites where the ligaments and tendons attach to the bones).
What is the plural of spondyloarthritis?
Spondyloarthritides is the plural of spondyloarthritis. 2,3 Spondyloarthritides are sometimes prefixed with the term seronegative in the literature; however, the prefix has been dropped because unlike rheumatoid arthritis (RA), SpAs are seronegative (rheumatoid factor (RF) and antinuclear antibody (ANA) negative) 5,6,7.
What is ankylosing spondylitis?
Ankylosing spondylitis, psoriatic arthritis, inflammatory bowel disease-associated inflammatory arthritis, and reactive arthritis all fall under this umbrella. These conditions are “seronegative” because laboratory evaluation (blood tests) for common causes of joint pain yields negative results.
What are undifferentiated spondyloarthropathy (USPA and axial SpA)?
Recent developments have expanded the concept of SpA to include undifferentiated spondyloarthropathy (USpA) and axial SpA. Undifferentiated SpA includes patients who are diagnosed with SpA, but do not fall into any specific subtype. 2 Axial SpA includes patients with both nonradiographic (AS without sacroiliitis) and with radiographic findings. 30